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David B. Stoll, MD; Paul Ruschak, MD; Young Kauh, MD; John Martin, MD; Herbert Luscombe, MD

Arch Dermatol. 1981;117(6):360-361.

Abstract
• A 54-year-old black woman with oculocutaneous albinism was found to have a lentigo maligna and, subsequently, a pigmented compound nevus on non-sun-exposed areas of her body. The diagnosis for these lesions was confirmed by the results of histopathologic study. To our knowledge, this is the first such case reported in the literature. This patient reemphasizes the fact that melanoma development is dependent on the presence of melanocytes, but not necessarily on melanogenesis. We propose that the rarity of melanomas in these patients may be caused by the protective effect of unknown systemic factors.

(Arch Dermatol 1981;117:360-361)

Author Affiliations
From the Departments of Medicine (Drs Stoll and Martin) and Dermatology (Drs Ruschak, Kauh, and Luscombe), Thomas Jefferson University Hospital, Philadelphia.

Footnotes
Accepted for publication Nov 26, 1980.

Reprint requests to Box 30, Thomas Jefferson University Hospital, Philadelphia, PA 19107 (Dr Stoll).

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ABSTRACT