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Werner's Syndrome With Associated Malignant Neoplasms
Randall P. Hrabko, MD;
Halina Milgrom, MD;
Robert Allen Schwartz, MD, MPH
Arch Dermatol. 1982;118(2):106-108.
Abstract
Werner's syndrome is an autosomal recessive disease characterized by juvenile cataracts, scleroderma-like skin changes, and a high incidence of neoplasms. A 57-year-old man had Werner's syndrome associated with a fibrosarcoma of the mediastinum and multiple basal cell epitheliomas. In two of these basal cell epitheliomas, since the sclerotic skin made it difficult to assess the extent of the tumor, microscopically controlled excision (Mohs' chemosurgery technique) was employed.
(Arch Dermatol 1982;118:106-108)
Author Affiliations
From the Department of Dermatology, Roswell Park Memorial Institute, Buffalo (Drs Hrabko, Milgrom, and Schwartz); and the Department of Dermatology, University of California School of Medicine and Veterans Hospital, San Francisco (Dr Schwartz).
Footnotes
Accepted for publication May 18, 1981.
Reprint requests to Dermatology Service (190), 4150 Clement St, San Francisco, CA 94121 (Dr Schwartz).
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