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Antoinette F. Hood, MD; Gary L. Hardegen, MD; Alfredo R. Zarate, MD; Thomas P. Nigra, MD; Michael C. Gelfand, MD

Arch Dermatol. 1982;118(2):85-88.

Abstract
• Hyperkeratosis follicularis et parafollicularis in cutem penetrans, or Kyrle's disease, is a rare dermatologic entity with distinctive clinical and histopathologic features. Over a two-year period, nine cases of Kyrle's disease were observed among 200 patients receiving hemodialysis for chronic renal failure. This observation suggests an association between Kyrle's disease and renal disease that, to our knowledge, has not previously been reported.

(Arch Dermatol 1982;118:85-88)

Author Affiliations
From the Divisions of Dermatology (Drs Hood, Hardegen, and Nigra) and Nephrology (Dr Zarate), Washington Hospital Center and Georgetown University Hospital (Dr Gelfand), Washington, DC. Dr Hood is now with the Department of Dermatology, The Johns Hopkins Medical Institutions, Baltimore.

Footnotes
Accepted for publication April 23, 1981.

Reprint requests to Department of Dermatology, The Johns Hopkins Medical Institutions, 601 N Wolfe St, Baltimore, MD 21205 (Dr Hood).

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