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Alexander Berman, MD; Sidney Herszenson, MD; Richard K. Winkelmann, MD, PhD

Arch Dermatol. 1982;118(2):93-96.

Abstract
• Progressive involution and subsequent regression of a plaque that showed the characteristic histologic findings of solitary lichen planus-like keratosis were observed in five patients. In each lesion, involution took place during a fourto eight-week period. In four patients, the lesion arose in a preexisting pigmented macule. Evolution into a plaque-like lesion coincided with the development of the inflammatory process. Origin from a preexisting lesion suggests that the lichenoid plaque is not an independent entity but a stage in the involution of the preexisting pigmented macule. The lichenoid inflammatory process resembles a delayed hypersensitivity reaction and seems to represent a cell-mediated rejection reaction.

(Arch Dermatol 1982;118:93-96)

Author Affiliations
From the Milwaukee Skin Center (Drs Berman and Herszenson); the Medical College of Wisconsin, Milwaukee (Dr Berman); and the Mayo Clinic and Mayo Foundation, Rochester, Minn (Dr Winkelmann).

Footnotes
Accepted for publication April 2, 1981.

Reprint requests to Milwaukee Skin Center, 7400 W Brown Deer Rd, Milwaukee, WI 53223 (Dr Berman).

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