This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (36)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Comparative Study of 113 Patients

Gustav Mahrle, MD; Sabine Meyer-Hamme, MD; Helmut Ippen, MD

Arch Dermatol. 1982;118(2):97-100.

Abstract
• This study reports comparative results of the effects of an aromatic retinoid, etretinate (RO 10-9359), on various disorders of the skin and mucous membranes. One hundred thirteen patients suffering from psoriasis, lichen planus, keratosis follicularis, and various other disorders were treated and examined. The patients received 25 to 100 mg/day of oral etretinate for up to 30 months. Patients with erythrodermic psoriasis, pustular psoriasis, and keratosis follicularis showed the best response. The conditions of patients with psoriasis vulgaris, palmoplantar psoriasis, and lichen planus also improved, but less impressively. The mucous membrane lesions of lichen planus and leukoplakia showed only moderate improvement. The most striking adverse clinical reactions observed were cheilitis (70%), dryness of the mucous membranes (27%), and hair loss (27%).

(Arch Dermatol 1982; 118:97-100)

Author Affiliations
From the Dermatological Clinic, University of Göttingen, West Germany.

Footnotes
Accepted for publication May 2, 1981.

Reprint requests to Dermatological Clinic, University of Göttingen, V.-Siebold-Strabe 3, D-3400 Göttingen, West Germany (Dr Mahrle).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Treatment of Lichen Planus: An Evidence-Based Medicine Analysis of Efficacy
Cribier et al.
Arch Dermatol 1998;134:1521-1530.
ABSTRACT | FULL TEXT