This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Marvin Lutzner, MD; Roger Kuffer, MD, DDS; Claudine Blanchet-Bardon, MD; Odile Croissant, PhD

Arch Dermatol. 1982;118(6):393-399.

Abstract
• We have observed four patients with oral papillomas. Two children had oral mucosal lesions characteristic of focal epithelial hyperplasia, a young man had common, wart-like lesions on his hard palate, and a male immunosuppressed renal allograft recipient had condyloma-like lesions on his gingivae. Papillomavirus-like particles were seen by electron microscopy in lesions from both patients with focal epithelial hyperplasia. No structural antigens for human papillomavirus (HPV) 1, 2, 3, or 5 were found by immunofluorescent microscopy, but further evidence of the presence of a papillomavirus was found by immunoperoxidase microscopy using a cross-reacting sodium lauryl sulfate-disrupted bovine papillomavirus 1 anti-rabbit serum sample. The distinct histologic pattern seen in focal epithelial hyperplasia suggests that a yet undescribed HPV type might be associated with this disease. Histologic, ultrastructural, and immunofluorescent microscopy and restriction endonuclease analysis all gave evidence of HPV 2 in the palatal lesions in patient 3. Evidence of papillomavirus antigen was found by immunoperoxidase microscopy in the oral condylomas from our immunosuppressed patient.

(Arch Dermatol 1982;118:393-399)

Author Affiliations
From the Unité de l'Institut National de la Santé et de la Recherche Médicale U 190, Institut Pasteur (Drs Lutzner and Croissant) and Clinique Dermatologique, Hôpital St Louis (Drs Kuffer and Blanchet-Bardon), Paris.

Footnotes
Accepted for publication Aug 6, 1981.

Reprint requests to Unité des Papillomavirus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris 15, France (Dr Lutzner).

CiteULike    Connotea    Del.icio.us    Digg    Facebook    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Human Papillomavirus Type 16 in Bowenoid Papulosis, Intraoral Papillomas, and Squamous Cell Carcinoma of the Tongue
Lookingbill et al.
Arch Dermatol 1987;123:363-368.
ABSTRACT  

The Human Papillomaviruses: A Review
Lutzner
Arch Dermatol 1983;119:631-635.
ABSTRACT