 |
|
Verruciform Xanthoma in an Epithelial Nevus
Roberta F. Palestine, MD;
R. K. Winkelmann, MD, PhD
Arch Dermatol. 1982;118(9):686-691.
Abstract
• Verruciform xanthoma is an unusual lesion that was initially reported in 1971. Clinically, it is a verrucous, vascular, epithelial plaque or papillomatous growth commonly found on oral or mucosal tissues. Histologically, it is characterized by a verruciform epithelium with abundant parakeratosis and by foam cells occupying the vascularized dermal papillae. This is the second extramucosal verruciform xanthoma reported. Our patient had several unique features. She is the youngest patient described to date, her lesion is the largest reported, and the lesion occurred in an epithelial nevus-type eruption on a phocomelic extremity. Light and electron microscopic studies disclosed abnormal keratinization, mast cell proliferation, and the previously described foam cells. We believe that the verruciform xanthoma in our patient represents part of a reaction to the epithelial nevus occurring in association with a developmental anomaly.
(Arch Dermatol 1982;118:686-691)
Author Affiliations
From the Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minn.
Footnotes
Accepted for publication Dec 3, 1981.
Reprint requests to Section of Publications, Mayo Clinic, Rochester, MN 55905 (Dr Palestine).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
A Novel Somatic Mutation of the 3{beta}-Hydroxysteroid Dehydrogenase Gene in Sporadic Cutaneous Verruciform Xanthoma
Mehra et al.
Arch Dermatol 2005;141:1263-1267.
ABSTRACT
| FULL TEXT
Verruciform Xanthoman of the Scrotum
Kimura
Arch Dermatol 1984;120:1378-1379.
ABSTRACT
|
