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Alice Ma, MD; Maria Medenica, MD

Arch Dermatol. 1983;119(10):836-839.

Abstract
• A patient with generalized granuloma annulare experienced resolution of her lesions after six months of treatment with 1,500 mg/day of niacinamide. Niacinamide seems to be a reasonably safe drug that, even at relatively high doses, is associated with a low incidence of side effects. The participation of a delayed hypersensitivity reaction in the pathogenesis of granuloma annulare and possible mechanisms involving niacinamide in this type of reaction are discussed.

(Arch Dermatol 1983;119:836-839)

Author Affiliations
From the Section of Dermatology, Department of Medicine, University of Chicago Pritzker School of Medicine.

Footnotes
Accepted for publication Sept 2, 1982.

Reprint requests to 950 E 59th St, Box 409, Chicago, IL 60637 (Dr Ma).

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