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Phenytoin Therapy for Junctional Epidermolysis Bullosa
Rhonda B. Rogers, MD;
Kim B. Yancey, MD;
Bruce S. Allen, MD;
Margaret F. Guill, MD
Arch Dermatol. 1983;119(11):925-926.
Abstract
• Junctional epidermolysis bullosa (JEB) is a recessively inherited mechanobullous disease characterized by neonatal onset of blisters, healing without scarring or milium formation, dystrophic nails, and internal involvement in some patients. Several treatment modalities have been tried, including systemic corticosteroids and oral vitamin E, but no form of therapy has been uniformly successful. We describe a patient with JEB treated with phenytoin, followed by improvement in his skin lesions.
(Arch Dermatol 1983;119:925-926)
Author Affiliations
From the Departments of Dermatology (Dr Rogers and Allen) and Pediatrics (Dr Guill), Medical College of Georgia, Augusta, and the Dermatology Branch, National Cancer Institute, National Institutes of Health (Dr Yancey), Bethesda, Md.
Footnotes
Accepted for publication Oct 18, 1982.
Reprint requests to Department of Dermatology, Medical College of Georgia, Augusta, GA 30912 (Dr Rogers).
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