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Change in Malar Thermal Circulation Index During Provoked Flushing Reactions

Jonathan K. Wilkin, MD

Arch Dermatol. 1983;119(3):211-214.

Abstract
• The effects of clonidine hydrochloride, an agent effective in suppressing other types of flushing reactions, were investigated in patients with erythematotelangiectatic rosacea. Clonidine hydrochloride, 0.05 mg, was given orally twice daily for two weeks. Mean arterial BP was not altered during clonidine treatment. Flushing reactions provoked with water at 60 °C, red wine, and chocolate were not suppressed during clonidine treatment. Clonidine did lead to malar hypothermia. It may be that any treatment benefit obtained from the reduction in vascular reactivity by clonidine in rosacea is offset by the malar hypothermia.

(Arch Dermatol 1983;119:211-214)

Author Affiliations
From the Department of Dermatology, University of Texas Medical School at Houston. Dr Wilkin is now with The Dermatology Section, Veterans Administration Medical Center, Richmond, Va.

Footnotes
Accepted for publication May 16, 1982.

Reprint requests to Dermatology Section (111), Veterans Administration Medical Center, 1201 Broad Rock Rd, Richmond, VA 23224 (Dr Wilkin).

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