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Richard Johnson, MD; Bernard P. Nusbaum, MD; Stephen N. Horwitz, MD; Phillip Frost, MD

Arch Dermatol. 1983;119(8):660-663.

Abstract
• Fifty hospitalized dermatology patients participated in a study to evaluate the transfer of topically applied tetracycline hydrochloride-containing fluorescent ointments, creams, lotions, and tinctures from various sites of application. Patients were examined with a Wood's lamp 24 hours after application to determine the sites and areas of transfer. The topically applied medications did not remain confined to sites of initial application. The anatomic sites of initial application determined the pattern of transfer. Certain patterns of transfer were characteristic among groups of patients and for specific patients. The vehicle of the topical preparation greatly influenced the extent and sites of transfer.

(Arch Dermatol 1983;119:660-663)

Author Affiliations
From the Department of Dermatology, Mount Sinai Medical Center, Miami Beach, Fla.

Footnotes
Accepted for publication Aug 6, 1982.

Presented at the 107th annual meeting of the Florida Medical Association, Hollywood, Fla, May 2, 1981, and the ninth annual midwinter assembly of American Physicians Fellowship, Inc, Hollywood, Fla, Feb 26, 1982.

Reprint requests to Department of Dermatology, Mount Sinai Medical Center, 4300 Alton Rd, Miami Beach, FL 33140 (Dr Johnson).

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