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Serum Triglyceride Elevation Following High-Dose Vitamin A Treatment for Pityriasis Rubra Pilaris
John C. Murray, MD;
Robert S. Gilgor, MD;
Gerald S. Lazarus, MD
Arch Dermatol. 1983;119(8):675-676.
Abstract
• We describe two patients with pityriasis rubra pilaris in whom hypertriglyceridemia developed following the oral administration of high-dose vitamin A (retinol). The effects of transient hypertriglyceridemia are unknown, as both patients tolerated high-dose vitamin A therapy with minor, if any, other side effects. Both patients had minimal clinical improvement with this therapy. Patients being treated with 1,000,000 IU of vitamin A each day for ten to 14 days should have frequent determinations of serum lipid levels and liver function during the period of drug administration.
(Arch Dermatol 1983;119:675-676)
Author Affiliations
From the Division of Dermatology, the Department of Medicine, Duke University Medical Center, Durham, NC.
Footnotes
Accepted for publication Feb 26, 1983.
Reprints not available.
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