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Graft-v-Host Disease
MAJ William D. James, MC;
COL Richard B. Odom, MC
Arch Dermatol. 1983;119(8):683-689.
Abstract
• Increasing numbers of persons are undergoing bone marrow transplantation for severe aplastic anemia and hematologic malignant neoplasms, and the proportion of those surviving has increased. Graft-v-host disease (GVHD) will, therefore, be seen with increasing frequency in the future. Graft-v-host disease occurs when immunocompetent donor lymphoid cells recognize and attack antigens of the immunocompromised host. We describe the clinical and histologic appearance of the different types of GVHD and discuss treatment, pathogenesis, and prevention of this entity.
(Arch Dermatol 1983;119:683-689)
Author Affiliations
USA; USA
From the Dermatology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco. Dr James is currently with the Keller Army Hospital, West Point, NY.
Footnotes
Accepted for publication Oct 9, 1982.
The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.
Reprint requests to Technical Publications Editor, Letterman Army Medical Center, Presidio of San Francisco, CA 94129 (Dr Odom).
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