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Josiane S. Lederman, MD; Thomas B. Fitzpatrick, MD; Arthur J. Sober, MD

Arch Dermatol. 1984;120(11):1449-1452.

Abstract
• Skin markings and pathologic findings in 105 patients with cutaneous melanoma were reviewed to determine relationship between clinical findings, pathologic findings, and prognosis. Lesions with decreased or absent markings are significantly thicker than those with increased or normal markings and therefore carry a worse prognosis. Loss of skin markings is a late sign of melanoma and should not be relied on as an aid in early diagnosis.

(Arch Dermatol 1984;120:1449-1452)

Author Affiliations
From the Department of Dermatology, Massachusetts General Hospital (Drs Lederman, Fitzpatrick, and Sober) and Harvard Medical School (Drs Fitzpatrick and Sober), Boston.

Footnotes
Accepted for publication May 31, 1984.

Reprint requests to Department of Dermatology, Massachusetts General Hospital, Boston, MA 02114 (Dr Sober).

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ABSTRACT