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Some Quantitative Aspects

Shigeo Nonaka, MD; Kays H. Kaidbey, MD; Albert M. Kligman, MD, PhD

Arch Dermatol. 1984;120(5):609-612.

Abstract
• The magnitude and time course of UV radiation-induced photoprotection was investigated in fair-skinned volunteers. Resistance to sunburn was evident three days following single exposures to UV-B, reached a maximum by seven days, and declined gradually over a period of 30 to 40 days. Both the magnitude and time course of UV radiation-induced photoprotection were dose related. The maximal mean protection factor following an exposure to 2 minimal erythemal doses was 4.2. The present findings, along with earlier studies, suggest that there are pronounced spectral differences with regard to the induction of photoprotective adaptation and that UV-B wavelengths are the most effective.

(Arch Dermatol 1984;120:609-612)

Author Affiliations
From the Duhring Laboratories, Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia.

Footnotes
Accepted for publication Oct 2, 1983.

Reprints not available.

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