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Paper-Tape Occlusion of Anthralin PasteA New Outpatient Therapy for Psoriasis
Dale L. Pearlman, MD;
Jean Burns, RN;
Thomas C. Cannon, RN;
Curtis S. Engelhard, MS
Arch Dermatol. 1984;120(5):625-630.
Abstract
• We present a new method for the outpatient use of anthralin paste in the treatment of psoriasis. By instructing the patient to cover the nightly paste application with semipermeable paper tape, we devised a practical and easy method for home therapy. In a study of 12 patients with unresponsive plaque-type psoriasis, six responded with 90% or better clearing of treated sites and two with 70% clearing, compared with symmetrical control sites. Four patients showed no substantial improvement. The average duration of therapy was 11 weeks. A three-month reevaluation of the conditions of these patients disclosed that improvement had been substantially maintained. Despite the tape occlusion, irritation was a manageable problem, except in three patients who had to halt therapy. Although less effective than conventional inpatient anthralin paste regimens, this method is more cost-effective for those with limited plaque disease.
(Arch Dermatol 1984;120:625-630)
Author Affiliations
From the Department of Dermatology, Kaiser-Permanente Medical Center, Santa Clara, Calif (Dr Pearlman, Ms Burns, and Mr Cannon); and the Department of Health Care Applications, Santa Teresa Medical Center, San Jose, Calif (Mr Engelhard).
Footnotes
Accepted for publication July 26, 1983.
Reprint requests to Department of Dermatology, Kaiser-Permanente Medical Center, 900 Kiely Blvd, Santa Clara, CA 95051 (Dr Pearlman).
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