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Bent Staberg, MD; Per Klemp, MD; Jørgen Serup, MD

Arch Dermatol. 1984;120(6):741-743.

Abstract
• We measured the cutaneous blood flow in positive standard patch test reactions by use of the laser-Doppler technique. The results were compared with conventional visual readings to develop a quantitative method. Compared with the basal blood flow in negative or nontested sites, the blood flow was significantly increased about fivefold in the doubtful reactions (?+), and about tenfold in both weak (1+) and strong (2+) positive reactions. The blood flows in the 1+ and 2+ reactions did not differ significantly from each other. No 3+ positive reactions were measured. We conclude that this method might be used to separate negative, doubtful, and positive reactions, whereas weak and strong positive reactions have to be differentiated by other means.

(Arch Dermatol 1984;120:741-743)

Author Affiliations
From the Departments of Clinical Physiology and Dermatology, The Finsen Institute (Drs Staberg and Klemp), and Dermatology (with Connective Tissue and Research Laboratory), University of Copenhagen, Rigshospitalet (Dr Serup).

Footnotes
Accepted for publication June 4, 1983.

Reprint requests to Department of Clinical Physiology, The Finsen Institute, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark (Dr Staberg).

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