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Generalized Staphylococcal Scalded Skin Syndrome in an Anephric Boy Undergoing Hemodialysis
Stephen L. Borchers, MD;
Edward C. Gomez, MD, PhD;
R. Rivkah Isseroff, MD
Arch Dermatol. 1984;120(7):912-918.
Abstract
 Generalized staphylococcal scalded skin syndrome (SSSS) is a toxin-related epidermolytic disease that predominantly affects previously healthy infants and children younger than 5 years. In contrast, the majority of the reported adult cases have been associated with underlying diseases, suggesting that immunosuppression and renal insufficiency are important predisposing conditions for this age group. We report herein a case of adult-type SSSS in an anephric 10-year-old boy. Patients undergoing hemodialysis who have chronic renal failure may be uniquely predisposed to the SSSS by virtue of their decreased glomerular filtration rate, associated uremic immunodeficiency, and a high incidence of Staphylococcus aureus bacteremia.
(Arch Dermatol 1984;120:912-918)
Author Affiliations
From the Department of Dermatology, University of California, Davis. Dr Borchers is now with The Permanente Medical Group, Roseville, Calif.
Footnotes
Accepted for publication Feb 21, 1983.
Reprints not available.
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