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Clinical Findings, Associations, and Long-term Follow-up Evaluations

Pierre Y. Venencie, MD; R. K. Winkelmann, MD, PhD; Burton A. Moore, MD

Arch Dermatol. 1984;120(8):1032-1039.

Abstract
• In 16 patients with anetoderma, a clinicohistologic entity related to a local dermal defect of elastic tissue, old lesions did not heal, and new lesions often continued to form for many years, despite various forms of treatment. Systemic lupus erythematosus, which occurred in one patient, must be ruled out in patients with anetoderma. Discoid lupus erythematosus occurred later in one patient. Other associated findings, noted in one patient each, included cataract, congenital hip dislocation, congenital fusion of the vertebrae at C2-3, diverticulum of the midesophagus, Addison's disease (before the onset of anetoderma), and mitral valve prolapse. Our results and a review of the literature indicate that patients with anetoderma must be examined for associated eye, bone, heart, pulmonary, digestive tract, and endocrine abnormalities for a better assessment of their skin disorders.

(Arch Dermatol 1984;120:1032-1039)

Author Affiliations
From the Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minn. Dr Venencie is a visiting clinician from the Clinique Dermatologique (Pr A. Puissant), Hôpital St Louis, Paris.

Footnotes
Accepted for publication Aug 24, 1983.

Reprint requests to the Section of Publications, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr Venencie).

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