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  Vol. 120 No. 8, August 1984 TABLE OF CONTENTS
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Nail Involvement in Histiocytosis X

A 12-Year Retrospective Study

Penwadee Timpatanapong, MD; Phongjan Hathirat, MD; Parttraporn Isarangkura, MD, DSc

Arch Dermatol. 1984;120(8):1052-1056.


Abstract

• A retrospective study of nail involvement was made in 15 cases of histiocytosis X (HX). These included seven cases of Letterer-Siwe (LS) disease, four cases of Hand-Schüller-Christian disease, and four cases of eosinophilic granuloma seen at Ramathibodi Hospital, Bangkok, Thailand, during the years 1970 to 1981. Nail involvement was found in three patients with LS disease, two of whom showed fingernail and toenail dystrophy with onycholysis and subungual hyperkeratosis. Paronychial erythema and swelling with small pustules underneath some nails were seen in both of the latter patients. The remaining patient showed subungual purpura of all fingernails and toenails with slight thickening of some fingernails. The nail changes in one patient responded well to cytotoxic therapy but recurred when the disease progressed. Nail involvement seems to be one of the unfavorable prognostic signs in HX.

(Arch Dermatol 1984;102:1052-1056)



Author Affiliations

From the Dermatology Division, Department of Medicine (Dr Timpatanapong), and the Hematology Division, Pediatric Department (Drs Hathirat and Isarangkura), Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.


Footnotes

Accepted for publication June 10, 1983.

Read before the Fifth Regional (Asian-Australian) Conference of Dermatology, Manila, Philippines, May 18, 1982.

Reprint requests to Division of Dermatology, Department of Medicine, Ramathibodi Hospital, Mahidol University, Rama 6 Rd, Bangkok 10400, Thailand (Dr Timpatanapong).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Nail and Scalp Lesions in a Man With Diabetes Insipidus
Munro and Morton
Arch Dermatol 1998;134:1477-1482.
FULL TEXT  

Nail Changes in Histiocytosis X
Alsina et al.
Arch Dermatol 1991;127:1741-1741.
ABSTRACT  





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