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  Vol. 120 No. 8, August 1984 TABLE OF CONTENTS
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Scanning Electron Microscopic Evaluation of Tinea Versicolor

Effects of Treatment With Miconazole Nitrate and Clotrimazole

David H. McDaniel, MD; William A. Welton, MD

Arch Dermatol. 1984;120(8):1057-1058.


Abstract

• A study of tinea versicolor organisms was conducted in one patient by scanning electron microscopy. Morphologic changes in the organisms during treatment with topical clotrimazole and miconazole nitrate consisted of initial wrinkling of the surface, followed by fragmentation. These changes may have reflected cell wall alterations resulting from inhibited ergosterol synthesis induced by both treatment agents. The two drugs were effective in eliminating the organisms.

(Arch Dermatol 1984;120:1057-1058)



Author Affiliations

From the Department of Medicine, Section of Dermatology, West Virginia University, Morgantown.


Footnotes

Accepted for publication Feb 28, 1983.

Read before the Society of Investigative Dermatology, San Antonio, Tex, Nov 16, 1980.

Reprints not available.



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Skin Surface Electron Microscopy in Pityrosporum Folliculitis: The Role of Follicular Occlusion in Disease and the Response to Oral Ketoconazole
Hill et al.
Arch Dermatol 1990;126:181-184.
ABSTRACT  





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