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Successful Treatment With Sulfonamides in an Immunosuppressed Patient

Maj James D. Heironimus, MC; Maj Richard E. Winn, MC; Lt Col Cleve B. Collins, MC

Arch Dermatol. 1984;120(8):1061-1063.

Abstract
• A 52-year-old man, who had received immunosuppressive therapy for four years after renal transplantation, had a deep-set skin infection in his thigh caused by Mycobacterium chelonei. In vitro studies indicated that the organism was resistant to antimycobacterial agents but potentially sensitive to high-dose sulfonamide therapy. Repeated surgical excisions failed to eradicate the infection, as documented by histopathologic examination. The combination of a reduced dose of immunosuppressive medication and the administration of high-dose sulfonamide therapy resulted in clinical recovery.

(Arch Dermatol 1984;120:1061-1063)

Author Affiliations
USAF; USAF; USAF

From the Nephrology Service (Drs Heironimus and Collins) and the Infectious Disease Service (Dr Winn), Wilford Hall USAF Medical Center, Lackland AFB, Tex.

Footnotes
Accepted for publication Feb 26, 1983.

Reprint requests to the Infectious Disease Service, Wilford Hall USAF Medical Center, Lackland AFB, TX 78236 (Dr Winn).

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