Cutaneous nonpulmonary Mycobacterium chelonei infection. Successful treatment with sulfonamides in an immunosuppressed patient
J. D. Heironimus, R. E. Winn and C. B. Collins
A 52-year-old man, who had received immunosuppressive therapy for four
years after renal transplantation, had a deep-set skin infection in his
thigh caused by Mycobacterium chelonei. In vitro studies indicated that the
organism was resistant to antimycobacterial agents but potentially
sensitive to high-dose sulfonamide therapy. Repeated surgical excisions
failed to eradicate the infection, as documented by histopathologic
examination. The combination of a reduced dose of immunosuppressive
medication and the administration of high-dose sulfonamide therapy resulted
in clinical recovery.