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Isotretinoin vs Etretinate Therapy in Generalized Pustular and Chronic Psoriasis
Ronald L. Moy, MD;
Timothy P. Kingston, MB, MRCP;
Nicholas J. Lowe, MD, FRCP
Arch Dermatol. 1985;121(10):1297-1301.
Abstract
• The clinical response to isotretinoin (13-cis-retinoic acid) in 11 patients with generalized pustular psoriasis was evaluated. Control of pustulation and systemic symptoms was achieved in ten cases, but additional therapy was required to produce complete clearing of all psoriatic lesions. Also, the efficacy of isotretinoin and etretinate in the treatment of chronic plaque psoriasis was compared in 29 patients. Isotretinoin was found to be less effective than etretinate in the treatment of chronic plaque psoriasis.
(Arch Dermatol 1985;121:1297-1301)
Author Affiliations
From the Division of Dermatology, UCLA School of Medicine, Los Angeles.
Footnotes
Accepted for publication July 11, 1985.
Read in part before the National Clinical Dermatology Conference of the American Academy of Dermatology, Chicago, June 23, 1984.
Reprint requests to Division of Dermatology, UCLA School of Medicine, Los Angeles, CA 90024 (Dr Lowe).
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