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Michael Bigby, MD; Robert S. Stern, MD; JudyAnn Bigby, MD

Arch Dermatol. 1985;121(11):1394-1399.

Abstract
• In a survey of 62 clinical trials published in four dermatology journals, recommended methodology was reported 41% of the time. Of the 62 trials, 31 were open drug trials and 27 were controlled trials. Forty-one percent of 13 recommended methodologic items were reported in these articles. The rate of reporting for these items ranged from 3% for power and method of randomization to 76% for loss to follow-up and the use of a control group. There were no differences among journals in reporting methods used. Investigators and editors are encouraged to improve the reporting and use of recommended methodology in clinical trials published in the dermatologic literature.

(Arch Dermatol 1985;121:1394-1399)

Author Affiliations
From the Department of Dermatology and the Charles A. Dana Research Institute, Beth Israel Hospital and Harvard Medical School (Drs M. Bigby and Stern); and the Department of Medicine, Division of General Internal Medicine, Brigham and Women's Hospital and Harvard Medical School (Dr J. Bigby), Boston.

Footnotes
Accepted for publication May 24, 1985.

Reprint requests to Department of Dermatology, Beth Israel Hospital, Boston, MA 02215 (Dr M. Bigby).

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