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Homer S. Black, PhD; Fred F. Castrow II, MD; Janette Gerguis

Arch Dermatol. 1985;121(3):348-349.

Abstract
• A sample of dinitrochlorobenzene, determined by gas-liquid chromatography and mass spectrometry to be greater than 98% pure, was tested in the Salmonella typhimurium plate assay. The chemical evoked a marked mutagenic response at all concentrations tested (3 to 150 µg per plate). These results confute the suitability of this agent for the treatment of benign skin disorders.

(Arch Dermatol 1985;121:348-349)

Author Affiliations
From the Photobiology Laboratory, Veterans Administration Medical Center (Dr Black and Ms Gerguis), and the Department of Dermatology, Baylor College of Medicine (Drs Black and Castrow), Houston.

Footnotes
Accepted for publication Feb 25, 1984.

Reprints not available.

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