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A Clinical, Histologic, and Ultrastructural Study

Ramon L. Sanchez, MD; Sharon S. Raimer, MD; Frank Peltier, MD; John Swedo

Arch Dermatol. 1985;121(5):626-631.

Abstract
• Electron microscopic examination in a case of papular xanthoma revealed the presence of myelinlike laminated bodies in the cytoplasm of the foam cells. To our knowledge, similar bodies have been described in large numbers in only two cases of congenital self-healing histiocytosis and one case of generalized eruptive histiocytoma. The presence of laminated bodies may be a morphologic characteristic of papular xanthoma. However, this possibility should be confirmed by identification of the same inclusions in other cases of this disease.

(Arch Dermatol 1985;121:626-631)

Author Affiliations
From the Departments of Dermatology (Drs Sanchez, Raimer, and Peltier) and Pediatrics (Dr Raimer), and the Division of Surgical Pathology (Dr Sanchez and Mr Swedo), The University of Texas Medical Branch, Galveston.

Footnotes
Accepted for publication Oct 31, 1984.

Reprint requests to the Division of Surgical Pathology, The University of Texas Medical Branch, Galveston, TX 77550 (Dr Sanchez).

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