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A New Variant Characterized by Progressive Symmetrical Centripetal Involvement With Scarring

Jo-David Fine, MD; Lamar S. Osment, MD; Steffen Gay, MD

Arch Dermatol. 1985;121(8):1014-1017.

Abstract
• A patient is reported with a form of epidermolysis bullosa, hitherto undescribed to the best of our knowledge, characterized by the slow centripetal progression of symmetrical blister formation, milia, scarring, atrophy, and nail dystrophy. Electron microscopy, immunofluorescence mapping, and KF-1 monoclonal antibody studies confirm this disease to be a form of dystrophic epidermolysis bullosa, probably of autosomal recessive transmission despite the absence of acral deformities, contractures, mucosal involvement, and growth retardation.

(Arch Dermatol 1985;121:1014-1017)

Author Affiliations
From the Departments of Dermatology (Drs Fine and Osment) and Medicine (Dr Gay), University of Alabama at Birmingham School of Medicine.

Footnotes
Accepted for publication Feb 5, 1985.

Reprint requests to Department of Dermatology, University of Alabama at Birmingham, University Station, Box 76, Birmingham, AL 35294 (Dr Fine).

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