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Angela Peterman, MD; Myles, MD; Steven Staal, MD; Bradley, MD; Howard Striecher, MD; Jörg Schüpbach, MD; Lionel Resnick, MD

Arch Dermatol. 1986;122(5):568-571.

Abstract
• Human T-cell lymphotropic virus type I (HTLV-I) is a human retrovirus that can transform T-helper lymphocytes and is etiologically associated with adult T-cell lymphoma/leukemia. Mycosis fungoides represents a primary cutaneous lymphoma of helper T-cell origin, while chronic lymphocytic leukemia is generally considered to be a neoplastic B-lymphocyte disorder. Our patient had HTLV-I with coexistent mycosis fungoides and B-cell chronic lymphocytic leukemia. The concurrent lymphoid proliferations may represent HTLV-I-associated abnormalities of immunoregulation.

(Arch Dermatol 1986;122:568-571)

Author Affiliations
From the Departments of Dermatology (Drs Peterman and Jerdan) and Oncology (Dr Staal), The Johns Hopkins Medical Institutions, Baltimore; the Clinical Immunology Section, Gerontology Research Center, National Institute on Aging, Baltimore (Dr Bender); the Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Md (Drs Striecher and Schüpbach); and the Department of Dermatology, Mount Sinai Medical Center, Miami Beach, Fla (Dr Resnick).

Footnotes
Accepted for publication Dec 13, 1985.

Read before the Eastern Section meeting of the American Federation of Clinical Research, Baltimore, Sept 26, 1985.

Reprint requests to Department of Dermatology, The Johns Hopkins Medical Institutions, 600 N Wolfe St, Blalock 9, Baltimore, MD 21205 (Dr Peterman).

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