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Evaluation of Anthralin in the Treatment of Alopecia Areata
Virginia C. Fiedler-Weiss, MD;
Cunera M. Buys, MS
Arch Dermatol. 1987;123(11):1491-1493.
Abstract
• Anthralin cream 0.5% to 1.0% was used to treat 68 patients with severe alopecia areata. Therapy was relatively well tolerated, although all patients experienced pruritus and local erythema and scaling. Cosmetic response was seen in 17 (25%) of the patients, and was maintained during therapy in 12 (71%) of the 17 cosmetic responders. For the patients treated with 0.5% anthralin, the mean time to response (44 of 66 patients) was 11 weeks; the mean time to cosmetic response (13 of 66 patients) was 23 weeks. Duration of the current episode of hair loss did not correlate with cosmetic response. Compared with other currently available topical treatments, anthralin appears to be a reasonable therapeutic option for severe alopecia areata.
(Arch Dermatol 1987;123:1491-1493)
Author Affiliations
From the Department of Dermatology, University of Illinois College of Medicine, Chicago.
Footnotes
Accepted for publication May 7, 1987.
Presented in part at the Annual Meeting of the American Academy of Dermatology, New Orleans, Dec 9, 1986.
Reprint requests to Department of Dermatology (M/C 624), University of Illinois College of Medicine at Chicago, PO Box 6998, Chicago, IL 60690 (Dr Fiedler-Weiss).
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