This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Histologic and Ultrastructural Studies

Adelaide A. Hebert, MD; Nancy B. Esterly, MD; Karen A. Holbrook, PhD; John C. Hall, MD

Arch Dermatol. 1987;123(4):503-509.

Abstract
• A 4-month-old female infant had cutaneous and musculoskeletal changes consistent with the diagnosis of congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) syndrome. This syndrome encompasses abnormalities of several organ systems, and its origins and pathogenesis are poorly understood. This report describes an additional patient with this uncommon syndrome and includes light and electron microscopic studies of her skin lesions. Our patient's clinical features of meningocele, Shone's syndrome, and the electron microscopic findings have not previously been described in the American literature (to our knowledge) in association with this syndrome.

(Arch Dermatol 1987;123:503-509)

Author Affiliations
From the Departments of Pediatrics and Dermatology, Northwestern University Medical School and Children's Memorial Hospital, Chicago (Drs Hebert and Esterly); the Departments of Biological Structure and Medicine (Dermatology), University of Washington School of Medicine, Seattle (Dr Holbrook); and St Luke's Hospital, Kansas City, Mo (Dr Hall). Dr Hebert is now with the Departments of Dermatology and Pediatrics, University of Texas Medical School, Houston.

Footnotes
Accepted for publication Nov 23, 1986.

Reprint requests to Department of Dermatology, University of Texas Health Sciences Center, 6431 Fannin, Suite 1.204, Houston, TX 77030 (Dr Hebert).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

CHILD Syndrome in 3 Generations: The Importance of Mild or Minimal Skin Lesions.
Bittar et al.
Arch Dermatol 2006;142:348-351.
ABSTRACT | FULL TEXT  

Clinicopathologic Study of the Cornea in X-linked Ichthyosis
Kempster et al.
Arch Ophthalmol 1997;115:409-415.
ABSTRACT  

X-Linked Dominant Ichthyosis With Peroxisomal Deficiency: An Ultrastructural and Ultracytochemical Study of the Conradi-Hunermann Syndrome and Its Murine Homologue, the Bare Patches Mouse
Emami et al.
Arch Dermatol 1994;130:325-336.
ABSTRACT  

Peroxisomal Abnormality in Fibroblasts From Involved Skin of CHILD Syndrome: Case Study and Review of Peroxisomal Disorders in Relation to Skin Disease
Emami et al.
Arch Dermatol 1992;128:1213-1222.
ABSTRACT