This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Development Following Autologous and Syngeneic Bone Marrow Transplantation

Antoinette F. Hood, MD; Georgia B. Vogelsang, MD; Lisa P. Black, MD; Evan R. Farmer, MD; George W. Santos, MD

Arch Dermatol. 1987;123(6):745-750.

Abstract
• Graft-vs-host disease (GVHD) is a frequent complication of allogeneic bone marrow transplantation but has been infrequently reported following autologous or syngeneic bone marrow transplantation. Ninety-six autologous and 19 syngeneic marrow transplants were performed at our institution between July 1977 and March 1984. We report acute cutaneous GVHD occurring in seven patients who received autologous marrow and two patients who received marrow from an identical twin. All nine patients had clinically detectable eruptions and had skin biopsy specimens with histologic changes of grade 2 acute GVHD. Although most cases were mild and self-limiting, four patients required systemic corticosteroids to treat their disease. Thus, acute cutaneous GVHD was seen in approximately 8% of patients receiving autologous or syngeneic bone marrow transplants at our institution.

(Arch Dermatol 1987;123:745-750)

Author Affiliations
From the Departments of Dermatology (Drs Hood, Black, and Farmer) and the Bone Marrow Transplantation Program of The Johns Hopkins Oncology Center (Drs Vogelsang and Santos), The Johns Hopkins University School of Medicine, Baltimore.

Footnotes
Accepted for publication Dec 17, 1986.

Reprint requests to Department of Dermatology, Blalock 913-D, The Johns Hopkins Medical Institutions, 600 N Wolfe St, Baltimore, MD 21205 (Dr Hood).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Results of syngeneic hematopoietic stem cell transplantation for acute leukemia: risk factors for outcomes of adults transplanted in first complete remission
Fouillard et al.
haematol 2008;93:834-841.
ABSTRACT | FULL TEXT  

Risk factors for syngeneic graft-versus-host disease after adult hematopoietic cell transplantation
Adams et al.
Blood 2004;104:1894-1897.
ABSTRACT | FULL TEXT  

The Graft-Versus-Lymphoma Effect: Fact, Fiction, or Opportunity?
Bishop
JCO 2003;21:3713-3715.
FULL TEXT  

Effect of nucleated marrow cell dose on relapse and survival in identical twin bone marrow transplants for leukemia
Barrett et al.
Blood 2000;95:3323-3327.
ABSTRACT | FULL TEXT  

Chemotherapy-Induced Eccrine Squamous Syringometaplasia: A Distinctive Eruption in Patients Receiving Hematopoietic Progenitor Cells
Valks et al.
Arch Dermatol 1997;133:873-878.
ABSTRACT  

Graft-vs.-Host Disease
Woo et al.
CROBM 1997;8:201-216.
ABSTRACT | FULL TEXT  

Lichenoid Graft-vs-Host Disease in an Autologous Bone Marrow Transplant Recipient
Martin et al.
Arch Dermatol 1995;131:333-335.
ABSTRACT  

Interface Dermatitis: How Specific Are Its Histopathologic Features?
LeBoit
Arch Dermatol 1993;129:1324-1328.
ABSTRACT  

Histologic Comparison of Autologous Graft-vs-Host Reaction and Cutaneous Eruption of Lymphocyte Recovery
Bauer et al.
Arch Dermatol 1993;129:855-858.
ABSTRACT  

Rashes in Immunocompromised Cancer Patients: The Diagnostic Yield of Skin Biopsy and Its Effects on Therapy
Chren et al.
Arch Dermatol 1993;129:175-181.
ABSTRACT  

Interleukin 2 and Granulocyte-Macrophage Colony-Stimulating Factor Induce a Perivascular Lymphocytic Infiltrate in a Skin Explant Model
Horn et al.
Arch Dermatol 1991;127:1789-1793.
ABSTRACT  

Syngeneic Bone Marrow Transplantation and Adoptive Transfer of Peripheral Blood Lymphocytes Combined with Zidovudine in Human Immunodeficiency Virus (HIV) Infection
Lane et al.
ANN INTERN MED 1990;113:512-519.
ABSTRACT  

Transfusion-Associated Graft-vs-Host Disease in Patients With Malignancies: Report of Two Cases and Review of the Literature
Decoste et al.
Arch Dermatol 1990;126:1324-1329.
ABSTRACT  

Acute Graft-vs-Host Disease in an Immunodeficient Newborn Possibly due to Cytomegalovirus Infection
Tawfik and Jimbow
Arch Dermatol 1989;125:1685-1688.
ABSTRACT  

Cutaneous Eruptions of Lymphocyte Recovery
Horn et al.
Arch Dermatol 1989;125:1512-1517.
ABSTRACT  

T-Lymphocyte Subsets in the Lesional Skin of Allogeneic and Autologous Bone Marrow Transplant Patients
Paller et al.
Arch Dermatol 1988;124:1795-1801.
ABSTRACT  

Effects of cyclosporine A on T cell development and clonal deletion
Jenkins et al.
Science 1988;241:1655-1658.
ABSTRACT