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Childhood Epidermolysis Bullosa AcquisitaDetection in a 5-Year-Old Girl
Richard Rubenstein, MD;
Nancy B. Esterly, MD;
Jo-David Fine, MD
Arch Dermatol. 1987;123(6):772-776.
Abstract
• A 5 girl with a blistering disease involving the skin and the oral, ocular, and anogenital mucosa is described. The initial clinical, histologic, and immunofluorescence findings suggested a diagnosis of cicatricial pemphigoid. However, immunoelectron microscopy demonstrated linear deposits of several immunoreactants within the sub-lamina densa region of the dermoepidermal junction, consistent with the diagnosis of epidermolysis bullosa acquisita. Although epidermolysis bullosa acquisita is considered a disease of adult onset, it should be included in the differential diagnosis of blistering diseases in children.
(Arch Dermatol 1987;123:772-776)
Author Affiliations
From the Departments of Dermatology (Drs Rubenstein and Esterly) and Pediatrics (Dr Esterly), Northwestern University Medical School, and Children's Memorial Hospital, Chicago, the Department of Dermatology, University of Alabama at Birmingham School of Medicine, and the Dermatology Section, Medical Service, Birmingham (Ala) Veterans Administration Medical Center (Dr Fine).
Footnotes
Accepted for publication Nov 27, 1986.
Reprints not available.
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