
Lindane Neurotoxic Reaction in Nonbullous Congenital Ichthyosiform Erythroderma
MAJ Stephen J. Friedman, MC
Arch Dermatol. 1987;123(8):1056-1058.
Abstract
A 3-year-old boy with nonbullous congenital ichthyosiform erythroderma with a four-month history of scabies was treated with a single dose of lindane cream. In a 48-hour period, he developed nausea and vomiting and also suffered from an epileptiform convulsion and muscular spasms. Seventy-two hours after application of the cream, his blood lindane level was 54 ng/mL. Caution should be exercised when using lindane in patients with compromised epidermal barrier function.
(Arch Dermatol 1987;123:1056-1058)
Author Affiliations
USA
From the Dermatology Service, Department of Internal Medicine, William Beaumont Army Medical Center, El Paso, Tex.
Footnotes
Accepted for publication Jan 14, 1987.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of Defense.
Reprints not available.
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