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Antigenic Features and Structural Correlates of Basement MembranesRelationship to Epidermolysis Bullosa
Jo-David Fine, MD
Arch Dermatol. 1988;124(5):713-717.
Abstract
• Numerous antigenic epitopes are present within the dermoepidermal junction of human skin. Using monoclonal antibodies, the distribution of these epitopes in ontogeny, wound healing, and epidermolysis bullosa are being defined. These studies provide insight into the pathogenic mechanisms involved and offer opportunities for prenatal and postnatal diagnosis.
(Arch Dermatol 1988;124:713-717)
Author Affiliations
From the Department of Dermatology, University of Alabama in Birmingham School of Medicine, and the Dermatology Section, Birmingham (Ala) Veterans Administration Medical Center.
Footnotes
Accepted for publication Sept 14, 1987.
Presented in part at the workshop on the Pathogenesis, Clinical Features, and Management of the Non-Dermatological Complications of Epidermolysis Bullosa, National Institutes of Health, Bethesda, Md, Sept 8, 1986.
Reprint requests to the Department of Dermatology, University of Alabama in Birmingham, University Station, Box 76, Birmingham, AL 35294 (Dr Fine).
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