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Sheetal Sapra, MD; Louis Weatherhead, MB, FRCPC

Arch Dermatol. 1989;125(12):1666-1669.

Abstract
• An indigent male patient presented with a widespread nodular eruption involving the torso and limbs. The differential diagnosis included nodular secondary syphilis, Kaposi's sarcoma, sarcoidosis, and lymphoma. Investigation confirmed secondary syphilis with positive cerebrospinal fluid serologic findings. Penicillin therapy produced a Jarisch-Herxheimer reaction despite pretreatment to diminish this. Discussion on the clinical features and treatment of syphilis is presented.

(Arch Dermatol. 1989;125:1666-1669)

Author Affiliations
From the Division of Dermatology, Ottawa (Canada) General Hospital.

Footnotes
Accepted for publication June 29, 1989.

Reprint requests to Division of Dermatology, Ottawa General Hospital, 501 Smyth Rd, Ottawa, Ontario, Canada K1H 8L6 (Dr Sapra).

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