 |
|
Immunosuppression in Men With Bowenoid Papulosis
Sherrie B. Feldman, MD, PhD;
F. Mack Sexton, MD;
Jerry D. Glenn, MD, PhD;
Donald P. Lookingbill, MD
Arch Dermatol. 1989;125(5):651-654.
Abstract
• The immune status of four men with bowenoid papulosis was evaluated. Each case had been refractory to multiple methods of treatment. Three of the men had other infections and demonstrated a depletion of T4-helper cells. Two of these patients were anergic on skin testing, and the third showed weak reactivity. The fourth patient, who had no evidence of additional infections, had a normal T4 value and T4/T8 ratio, but was anergic on skin testing. All the men were serologically negative for human immunodeficiency virus antibodies. One of the immunosuppressed patients developed squamous cell carcinoma of the tongue, which, along with his bowenoid papulosis, contained human papillomavirus 16 DNA. We suggest that patients with persistent bowenoid papulosis be investigated for altered immune status and followed up as potential candidates for the development of epithelial malignant neoplasms.
(Arch Dermatol 1989;125:651-654)
Author Affiliations
From the Division of Dermatology, the Departments of Medicine (Drs Feldman, Sexton, and Lookingbill), Pathology (Dr Sexton), and Surgery (Dr Glenn), College of Medicine, Pennsylvania State University, Hershey.
Footnotes
Accepted for publication June 15, 1988.
Reprints not available.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Successful Treatment of Bowenoid Papulosis in a 9-Year-Old Girl With Vertically Acquired Human Immunodeficiency Virus
Godfrey et al.
Pediatrics 2003;112:e73-76.
ABSTRACT
| FULL TEXT
Anogenital Flat Papules: REPORT OF A CASE
Carpenter-Kling and Jacyk
Arch Fam Med 1995;4:27-28.
Anogenital Flat Papules
Carpenter-Kling and Jacyk
Arch Dermatol 1994;130:1311-1312.
ABSTRACT
Human Papillomavirus: Current Concepts
Androphy
Arch Dermatol 1989;125:683-685.
ABSTRACT
|
