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Yolanda M. Peña, MD; Margaret M. Bason, MD; Jane M. Grant-Kels, MD

Arch Dermatol. 1990;126(2):195-198.

Abstract
• A basal cell carcinoma with prominent focal squamous differentiation of the right nasolabial fold resulted in leptomeningeal carcinomatosis, despite appropriate surgical excision of the primary lesion. The controversy surrounding the origin, diagnosis, and prognosis of a basal cell carcinoma with squamous differentiation is reviewed. Potential routes of metastasis leading to the subsequent leptomeningeal carcinomatosis are discussed.

(Arch Dermatol. 1990;126:195-198)

Author Affiliations
From the Department of Neurology (Dr Peña) and Division of Dermatology, Department of Medicine (Dr Grant-Kels), University of Connecticut Health Center, Farmington, and the Department of Medicine, Hartford (Conn) Hospital (Dr Bason).

Footnotes
Accepted for publication September 26, 1989.

Reprint requests to Division of Dermatology, L 2060, University of Connecticut Health Center, Farmington, CT 06032 (Dr Grant-Kels).

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