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Similarities to Melanoma: The Vancouver Mole Study

Richard P. Gallagher, MA; David I. McLean, MD; C. Paul Yang, MD; Andrew J. Coldman, PhD; Hulbert K. B. Silver, MD; John J. Spinelli, MSc; Marjorie Beagrie, MA

Arch Dermatol. 1990;126(6):770-776.

Abstract
• The association between prevalence of benign melanocytic nevi and a number of skin cancer risk factors was examined among 913 white Vancouver (Canada) school children aged 6 to 18 years. Subjects with light skin, with a propensity to burn rather than tan in the sun, and with numerous or severe sunburns in the previous 5 years had significantly higher nevus counts than individuals without these characteristics. Subjects who acquired deeper tans tended to have fewer nevi than those who did not tan. Finally, children who freckled had higher nevus counts than those who did not freckle. These findings in children are similar to those seen in studies of malignant melanoma among adults and suggest that strategies to reduce melanoma incidence should begin with young children.

(Arch Dermatol. 1990;126:770-776)

Author Affiliations
From the Divisions of Epidemiology, Biometry, and Occupation Oncology (Mr Gallagher, Drs Yang and Coldman, Mr Spinelli, and Ms Beagrie) and Dermatologic Oncology (Dr McLean) and the Department of Advanced Therapeutics (Dr Silver), Cancer Control Agency of British Columbia, and the Department of Health Care and Epidemiology (Mr Gallagher), the Division of Dermatology (Dr McLean), and the Department of Medicine (Dr Silver), University of British Columbia, Vancouver, Canada.

Footnotes
Accepted for publication January 30, 1990.

Reprint requests to Division of Epidemiology, Biometry, and Occupation Oncology, Cancer Control Agency of British Columbia, 600 W 10th Ave, Vancouver, British Columbia, Canada V5Z 4E6 (Mr Gallagher).

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