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Report of a Case and Review of the Literature

Eleanor E. Sahn, MD; Paul D. Garen, MD; Richard M. Silver, MD; John C. Maize, MD

Arch Dermatol. 1990;126(9):1198-1202.

Abstract
• A 46-year-old woman developed localized scleroderma after surgical manipulation of her silicone gel-filled breast prostheses. She developed firm, shiny plaques on her legs that progressed to involve the thighs. Histopathologic examination of a deep-skin biopsy specimen confirmed the diagnosis of scleroderma. On surgical removal of the silicone implants, and their replacement with saline-filled implants, the scleroderma gradually resolved. Histopathologic examination of the removed implant capsules revealed evidence of silicone leakage. All new female patients with scleroderma should be questioned and examined regarding augmentation mammoplasty. Until prospective studies are completed on the possible association between scleroderma and silicone breast implants, it would seem prudent to use the saline-filled, elastomeric envelope-type breast implant for augmentation mammoplasty rather than the silicone gel-filled implant.

(Arch Dermatol. 1990;126:1198-1202)

Author Affiliations
From the Departments of Dermatology (Drs Sahn and Maize) and Pathology and Laboratory Medicine (Drs Garen and Maize) and the Division of Rheumatology and Immunology, Department of Medicine (Dr Silver), Medical University of South Carolina, Charleston.

Footnotes
Accepted for publication March 27, 1990.

Reprint requests to Department of Dermatology, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC 29425-2215 (Dr Sahn).

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