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Allison L. Holm, MD; Lowell A. Goldsmith, MD

Arch Dermatol. 1991;127(1):91-95.

Abstract
• A 30-year-old woman with congenital rickets and autosomal recessive ichthyosis developed impetigo herpetiformis in the second trimester of her first pregnancy. This condition was temporally related to her discontinuation of vitamin D supplements and subsequent hypocalcemia. No associated systemic symptoms were observed, and a healthy baby was delivered prematurely at 34 weeks' gestation. This report supports the association between hypocalcemia and impetigo herpetiformis and raises theoretical questions regarding a relationship between vitamin D metabolism and various epidermal hyperproliferative states.

(Arch Dermatol. 1991;127:91-95)

Author Affiliations
From the Department of Dermatology, University of Rochester (NY) School of Medicine.

Footnotes
Accepted for publication July 27, 1990.

Reprint requests to Department of Dermatology, Box 697, University of Rochester School of Medicine, 601 Elmwood Ave, Rochester, NY 14642 (Dr Holm).

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