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Elise A. Olsen, MD

Arch Dermatol. 1991;127(2):197-201.

Abstract
• Six generic formulations of five topical steroids were compared for bioequivalence with their trade-name counterparts using an in vivo vasoconstriction assay. Two of six generic formulations were found to show significantly less vasoconstriction than the respective trade-name topical steroids. The issue of generic equivalence of topical steroids is discussed, with particular emphasis on the vagaries of the vasoconstriction assay.

(Arch Dermatol. 1991;127:197-201)

Author Affiliations
From the Division of Dermatology, Department of Medicine, Duke University Medical Center, Durham, NC.

Footnotes
Accepted for publication September 14, 1990.

The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the US government.

Reprint requests to Box 3294, Duke University Medical Center, Durham, NC 27710 (Dr Olsen).

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