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OncogenesThe Growth Control Genes
Steven R. Feldman, MD, PhD;
Mina Yaar, MD
Arch Dermatol. 1991;127(5):707-711.
Abstract
Genes that are involved in the development of cancer have been identified. These genes, called "oncogenes," are related to normal cellular genes called "proto-oncogenes," which code for proteins involved in the regulation of cellular growth and differentiation. Through the study of these genes, we now begin to assess prognosis of several malignant neoplasms. Moreover, specific inhibitors of oncogene activity have potential use in treatment regimens for cancer.
(Arch Dermatol. 1991;127:707-711)
Author Affiliations
From the Department of Dermatology, Medical University of South Carolina, Charleston (Dr Feldman); US Department of Agriculture, the Human Nutrition Research Center on Aging at Tufts University and Department of Dermatology, Tufts University School of Medicine, Boston, Mass (Dr Yaar).
Footnotes
Accepted for publication October 25, 1990.
Reprint requests to Department of Dermatology, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC 29425-2215 (Dr Feldman).
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