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Gwendolyn A. Crane, MD; Daina Variakojis, MD; Steven T. Rosen, MD; Amy M. Sands, MD; Henry H. Roenigk, Jr, MD

Arch Dermatol. 1991;127(7):989-994.

Abstract
• The development of cutaneous T-cell lymphoma is unusual in individuals with human immunodeficiency virus type 1 infection. We present four patients with cutaneous T-cell lymphoma and human immunodeficiency virus type 1 infection. Immunophenotyping of lymph node tissue in three of these patients revealed a predominance of T-suppressor cells. Possible causes for the development of cutaneous T-cell lymphoma in the presence of human immunodeficiency virus type 1 infection are discussed.

(Arch Dermatol. 1991;127:989-994)

Author Affiliations
From the Departments of Dermatology (Drs Crane and Roenigk), Pathology (Drs Variakojis and Sands), and Medicine, Section of Hematology/Oncology, Cancer Center (Dr Rosen), Northwestern University Medical School, Chicago, Ill. Dr Sands is now with the State University of New York at Buffalo Medical School and the Veterans Affairs Hospital, Buffalo, NY.

Footnotes
Accepted for publication January 13, 1991.

Presented in part at the International Symposium on Cutaneous T-Cell Lymphoma, October 19-21, 1989, Chicago, Ill.

Reprint requests to the Department of Dermatology, Northwestern University Medical School, 303 E Chicago Ave, Chicago, IL 60611 (Dr Roenigk).

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