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Albert M. Kligman, MD, PhD

Arch Dermatol. 1991;127(9):1375-1382.

Abstract
The central tenet of invisible dermatology is that visible lesions represent a late stage of development. The eye is an unreliable instrument for judging the normalcy of skin. In chronic widespread dermatoses, the uninvolved skin is at least physiologically abnormal. Recently healed skin is always abnormal. Recognition of occult changes will have a substantial impact on the prevention and treatment of diseases of the skin.

(Arch Dermatol. 1991;127:1375-1382)

Author Affiliations
From the University of Pennsylvania School of Medicine, Philadelphia.

Footnotes
Accepted for publication May 3, 1991.

Reprint requests to the Department of Dermatology, University of Pennsylvania School of Medicine, Room 226, Clinical Research Bldg, 422 Curie Blvd, Philadelphia, PA 19104-6142 (Dr Kligman).

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ABSTRACT