 |
|
Idiopathic CD4+ Lymphocyte DeficiencyReport of an Unusual Case Associated With Atopic Dermatitis and Allergic Contact Dermatitis and Review of the Literature
Anita L. Goodrich, MD;
Robert E. Tigelaar, MD;
Kalman L. Watsky, MD;
Peter W. Heald, MD
Arch Dermatol. 1993;129(7):876-878.
Abstract
• Background.—
Idiopathic CD4 lymphocyte deficiency is a newly described entity of apparently non-human immunodeficiency virus-associated helper T-cell depletion. The clinical spectrum continues to evolve, but, to date, it has included patients ranging from those with minimal symptoms to those who have died with acute opportunistic infections. Several individual cases have been previously reported, many with distinctive, primarily infectious, cutaneous manifestations.
Observations.—
We describe a patient with idiopathic CD4+ lymphocyte deficiency distinguished by a unique clinical presentation of atopic dermatitis exacerbated by contact urticaria and allergic contact dermatitis. She has a persistent markedly diminished CD4+ lymphocyte count (absolute count less than 50), no serologic evidence of, or risk factors for, human immunodeficiency virus infection, and no history of opportunistic infections.
Conclusions.—
We present a possible new cutaneous manifestation of idiopathic CD4+ lymphocyte disease and summarize the previously reported cases, with an emphasis on the cutaneous features.
(Arch Dermatol. 1993;129:876-878)
Author Affiliations
From the Department of Dermatology, Yale University School of Medicine, New Haven, Conn.
Footnotes
Accepted for publication April 1, 1993.
Presented in part before the 18th World Congress of Dermatology, New York, NY, June 16, 1992, and before the American Contact Dermatitis Society Meeting, San Francisco, Calif, December 4, 1992.
Reprint requests to Department of Dermatology, LCI 500, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510 (Dr Goodrich).
 CiteULike  Connotea  Delicious  Digg  Facebook  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Acute Erythroderma as an Exclusion Criterion for Idiopathic CD4+ T Lymphocytopenia
Griffiths et al.
Arch Dermatol 1994;130:1530-1533.
ABSTRACT
|
