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Mycosis Fungoides Palmaris et Plantaris
Kenneth S. Resnik, MD;
Gary R. Kantor, MD;
Stuart R. Lessin, MD;
Marshall E. Kadin, MD;
Lilian Chooback, PhD;
Harry S. Cooper, MD;
Eric C. Vonderheid, MD
Arch Dermatol. 1995;131(9):1052-1056.
Abstract
Background
Mycosis fungoides primarily localized to the palms and soles is rare and has been previously reported as cutaneous lymphoma in four patients or as Woringer-Kolopp disease in eight patients.
Observations
Four patients were initially diagnosed and treated unsuccessfully for various palmoplantar dermatitides until histopathologic findings revealed mycosis fungoides. Each case exhibited a clonal rearrangement of T-cell receptor gamma genes and immunohistochemical studies consonant with mycosis fungoides. All patients had limited skin involvement without evidence of extracutaneous involvement.
Conclusions
Mycosis fungoides palmaris et plantaris is an uncommon expression of mycosis fungoides that manifests primarily on the palms and soles and clinically may mimic various inflammatory palmoplantar dermatoses. A biopsy is recommended in the evaluation of recalcitrant palmoplantar dermatoses.
(Arch Dermatol. 1995;131:1052-1056)
Author Affiliations
From the Departments of Dermatology, Medical College of Pennsylvania and Hahnemann University, Philadelphia (Drs Resnik, Kantor, and Vonderheid); Departments of Dermatology, University of Pennsylvania, Philadelphia (Drs Lessin and Chooback), and the Philadelphia Veterans Administration Medical Center (Dr Lessin); and the Departments of Pathology, Beth Israel Hospital and Harvard Medical School, Boston, Mass (Dr Kadin), and Medical College of Pennsylvania and Hahnemann University (Dr Cooper).
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