This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Nitric Oxide and the Cutis

Abrar A. Qureshi, MBBS; Lisa H. Lerner, MD; Ethan A. Lerner, MD, PhD

Arch Dermatol. 1996;132(8):889-893.

Abstract
When the discoverer of dynamite (trinitrotoluene [TNT]), Alfred Nobel, was prescribed nitroglycerin for angina in 1895, he was certainly taken aback. Almost a century later, organic nitrates and their gaseous metabolic end product, nitric oxide (NO), were implicated in a vast array of biologically diverse activities.¹ About 10 years ago, a series of discoveries from different avenues of research converged on NO, thrusting it into the limelight as a neurotransmitter, vasodilator, toxin, and modulator of immune function and inflammation.² Nitric oxide has thus managed to capture the interest of scientists from a number of fields and holds center stage attention. Interest in NO among dermatologists has been slow to appear, however, and the literature on NO with respect to the skin is sparse when compared with the steep escalation in the number of articles published generally on NO since 1987 (Figure 1).

Author Affiliations
Massachusetts General Hospital, Charlestown, Mass

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Neuro-Immuno-Cutaneous-Endocrine Network: Relationship of Mind and Skin
O'Sullivan et al.
Arch Dermatol 1998;134:1431-1435.
ABSTRACT | FULL TEXT