Vulvar Melanoma in Childhood
Conleth A. Egan, MB, MRCPI;
R. Ralph Bradley, MD;
Valerie K. Logsdon, MD;
Bradley K. Summers, MD;
Gary R. Hunter, MD;
Sheryll L. Vanderhooft, MD
Arch Dermatol. 1997;133(3):345-348.
Abstract
| |
Background
Malignant melanoma is rarely diagnosed during childhood. Approximately 2% of malignant melanomas occur in patients younger than 20 years, with 0.3% to 0.5% of cases occurring in prepubescent children. In adult females malignant melanoma of the vulva and vagina is 100-fold less common than malignant melanoma of nongenital skin. Malignant melanoma of the vulva occurring in a child has been reported once before.
Observations
We report 2 cases of childhood vulvar malignant melanoma presenting in preteenage girls. In both cases, the lesions were asymptomatic enlarging hyperpigmented macules on the labium minus. In addition to features diagnostic of malignant melanoma, histological evidence of lichen sclerosus et atrophicus was identified in both lesions. Local excision with conservative margins was the treatment modality of choice in both cases, with good preservation of anatomic structure and function.
Conclusions
This report is of 2 cases of vulvar melanoma in childhood, a rare, yet potentially devastating, presentation of melanoma. Biopsies on suspicious pigmented lesions on the vulva of prepubescent children should be done to rule out malignant change.
Arch Dermatol. 1997;133:345-348
Author Affiliations
From the Departments of Dermatology and Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Melanocytic Proliferations Associated With Lichen Sclerosus
Carlson et al.
Arch Dermatol 2002;138:77-87.
ABSTRACT
| FULL TEXT
Vulvar Nevi, Lichen Sclerosus et Atrophicus, and Vitiligo
Carlson and Mihm
Arch Dermatol 1997;133:1314-1315.
ABSTRACT
|
