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Dayna G. Diven, MD; Susan E. Dozier, MD; Diane J. Meyer, MD; Edgar B. Smith, MD

Arch Dermatol. 1998;134:49-51.

Objective  To determine whether inflamed and uninflamed epidermoid cysts differ in the number and/or type of bacteria inhabiting them.

Design  A controlled study. We obtained aerobic and anaerobic bacterial culture specimens from 25 inflamed and 25 uninflamed epidermoid cysts.

Setting  A university medical center.

Patients  Nonimmunocompromised adults without recent systemic use of antibiotics.

Results  The 2 groups did not differ significantly with respect to number of bacterial isolates, "no growth" cultures, and aerobic, anaerobic, or potential pathogens cultured.

Conclusions  The microbiological milieu of inflamed epidermoid cysts is similar to that of uninflamed cysts. Possible mechanisms for inflammation are discussed.

From the Department of Dermatology, University of Texas Medical Branch, Galveston (Drs Diven and Smith), Austin Regional Clinic, Austin, Tex (Dr Dozier), and Marshfield Clinic, Chippewa Falls, Wis (Dr Meyer).

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