This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (20)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Dermatology  • Dermatologic Disorders  • Radiation Therapy  • Nevi  • Alert me on articles by topic  Social Bookmarking   What's this?

A Dermoscopic Study

Rainer Hofmann-Wellenhof, MD; H. Peter Soyer, MD; Ingrid H. Wolf, MD; Josef Smolle, MD; Sebastian Reischle, MD; Edgar Rieger, MD; Robert O. Kenet, MD, PhD; Peter Wolf, MD; Helmut Kerl, MD

Arch Dermatol. 1998;134:845-850.

Background  UV radiation can lead to clinical, histological, and ultrastructural changes in melanocytic nevi. In this study, we investigated whether exposure to 2 minimal erythema doses of UV radiation induces changes in the dermoscopic image of acquired melanocytic nevi.

Observations  Fifteen melanocytic nevi were exposed to 2 minimal erythema doses of UV radiation. Differences in dermoscopic parameters (asymmetry, border, erythema, and telangiectasias in the nevus; pigmentation; hypopigmented areas; presence, regularity, and sharpness of pigment network; and brown-black globules) in digital dermoscopic images taken before and 3, 7, 14, and 28 days after UV irradiation were scored. Three days after UV irradiation, the borders of nevi were more faded (P<.02), the nevi were darker brown (P<.02), the hypopigmented areas were smaller (P<.02), and the pigment network structures were more faded (P<.007) and less prominent (P<.02) than before UV irradiation. Seven days after UV irradiation, pigmented globules have also grown (P<.05). After 28 days, all parameters, except hypopigmented areas, were essentially the same as before UV irradiation.

Conclusion  UV irradiation of melanocytic nevi with 2 minimal erythema doses induces transient changes in their dermoscopic appearance that are sometimes suggestive of malignant melanoma.

From the Department of Dermatology, University of Graz, Graz, Austria (Drs Hofmann-Wellenhof, Soyer, I. H. Wolf, Smolle, Reischle, Rieger, P. Wolf, and Kerl); and the Department of Medicine, Cornell University Medical College, New York, NY (Dr Kenet).

CiteULike    Connotea    Del.icio.us    Digg    Facebook    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Using Dermoscopic Criteria and Patient-Related Factors for the Management of Pigmented Melanocytic Nevi
Zalaudek et al.
Arch Dermatol 2009;145:816-826.
ABSTRACT | FULL TEXT  

Nevus Type in Dermoscopy Is Related to Skin Type in White Persons
Zalaudek et al.
Arch Dermatol 2007;143:351-356.
ABSTRACT | FULL TEXT  

Dermoscopic Changes in Nevi After UV Irradiation
Journal Watch Dermatology 1998;1998:2-2.
FULL TEXT